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Sedentary lifestyles and behaviours are highly prevalent in society. Globally, a lack of physical activity is linked to increasing metabolic and neural diseases, and reduced quality of life.

According to T. Rody et al. 2022; A challenging lifestyle modification that is critically needed for modern societies
consists in decreasing sedentary habits

This exciting publication highlights the many neuralphysiology markers believed to improve brain health and prevent Alzheimers disease.

Alzheimer’s disease is a progressive, complex, multifactorial
neurodegenerative disease that remains with no cure. Despite
scientific advances in understanding the pathophysiology of AD,
most of the results obtained in clinical trials are disappointing.
There is an urgent need to develop strategies aimed at
preventing the progression of the disease and at reversing
cognitive impairment in AD patients…

In conclusion, exerkines are a group of promising molecules
that may underlie the beneficial effects of exercise in individuals
with AD.

The emerging neuroprotective
roles of exerkines in Alzheimer’s
disease
.” 2022. Tayna Rody, Julia A. De Amorim and
Fernanda G. De Felice. [frontiersin.org]

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